Mastitis in Dairy Cattle

Mastitis is characterized as a persistent, inflammatory reaction of the udder tissue in cows. This inflammatory response is commonly due to bacterial infection but may also occur as a result of chemical, mechanical or thermal injury. 

Mastitis is the most common disease in dairy cattle and the most costly to the dairy industry in the United States.  Clinical mastitis causes economic loss due to treatment costs, lost quarters, loss of animals and lost or discarded milk.  Subclinical mastitis may simply creep along quietly reducing milk production and quality until detected with a somatic cell count.  Estimated annual costs to the US dairy industry are between $1.7 and $2.0 billion dollars. 

Common contagious pathogens are Streptococcus agalactiae, Staphylococcus aureus, Mycoplasmas and Corynebacterium bovis.  Common environmental pathogens are Streptococcus uberis and Streptococcus dysgalactaciae, Escherichia coli and Klebsiella pneumoniae. 

Similar to the way healthcare acquired infections in people are transmitted in our hospitals and clinics, mastitis is often transmitted by contact with the milking machine and through contaminated hands and materials. 

At Zurex PharmAgra, we have acquired a new non-antibiotic antimicrobial technology, which has demonstrated significant efficacy and safety in preventing healthcare acquired infections in medical clinics, and applied it to the dairy and veterinary industries.  Through targeted formulation and product development efforts, we have taken this new pharmaceutical technology and developed effective, non-iodine based, broad spectrum antimicrobial products in the teat dip, teat sealant and pre-surgical skin preparation categories. 



ZuraLac™ is specifically formulated to sanitize and protect teats from mastitis causing organisms, and protect teat skin tissue from harsh environmental conditions.


ZuraLac can be used as a pre and post milking teat treatment and is available in sprayable, foaming, dipping, high emollient, low drip and winter formulations.


ZuraSeal is an innovative, antimicrobial, external teat sealant designed to protect the dairy cow during the most vulnerable periods of the drying out cycle.


VetPrep is a topical, antimicrobial, presurgical skin preparation. It has been shown to be effective and safe in two pilot clinical trials performed per methodology  specified in the FDA Tentative Final Monograph for Effectiveness Testing of a Patient Preoperative Skin  Preparation.


See more of the preclinical and clinical data for our technology on our publications page.

Zurex PharmAgra Products

Introducing the ZuraLac™ family of sanitizing and moisturizing teat treatments that provide a wide spectrum of bacteria protection and are extremely gentle on the skin. We are also developing ZuraSeal™ for protection during the drying out period and VetPrep™, a presurgical skin preparation for agricultural animal and veterinary applications.